The annotation states that Augmentin should be drunk for 5-7 days. With a longer intake, dysbiosis and other negative consequences of antibiotic therapy may occur. But what should a person do if the course of Augmentin treatment is over, a marked improvement in well-being appears, but the complete disappearance of pathological symptoms did not occur. If you stop taking the antibiotic, then complications and the transition of the disease into a chronic form are possible. Can you buy augmentin online
To avoid this, there are several options: under the supervision of a doctor, Augmentin continues to be taken for up to 2 weeks; “step-by-step” therapy is carried out - first injections are made, and then Augmentin is prescribed a suspension or tablets (children under the age of twelve are allowed only a liquid dosage form); an analogue is selected that acts on the body in the same way as Augmentin, but has a different composition (there are many analogues that match the healing qualities of Augmentin). Read also: List of narcotic drugs Which of the options for continuing therapy will be chosen is decided individually. But you can’t drink Augmentin on your own or give a medicine to a child for more than a week - uncontrolled medication leads to negative consequences.
When prescribing a medication, you always need to clarify the duration of taking Augmentin. If complete recovery has not occurred within a week, then you should consult your doctor about further therapy. It is not recommended to drink Augmentin on one's own for a long time until the symptoms disappear completely - undesirable consequences may arise from prolonged use of the antibiotic.
It can be expected that inhibitors of microsomal oxidation will increase the concentration of amlodipine in plasma, increasing the risk of side effects, and inducers of microsomal enzymes of the liver will decrease. Cimetidine: with the simultaneous use of amlodipine with cimetidine, the pharmacokinetics of amlodipine does not change. Grapefruit juice: simultaneous single intake of 240 ml of grapefruit juice and 10 mg of amlodipine inside is not accompanied by a significant change in the pharmacokinetics of amlodipine. Unlike other BMCC, the clinically significant interaction of the drug Amlodipine (III generation BMCC) was not found when combined with non-steroidal anti-inflammatory drugs (NSAIDs), especially indomethacin.
Ecoclave (Amoxicillin + Clavulanic acid) tablets 250 mg + 125 mg, 15 pcs.: Pharmacological properties Broad-spectrum antibacterial. http://www.rxwiki.com/augmentin
It blocks the synthesis of peptidoglycan of the membrane of microbial cells (amoxicillin), inhibits beta-lactamases (clavulanic acid). Clavulanic acid forms a stable inactivated complex with these enzymes and protects amoxicillin from the loss of antibacterial activity caused by the production of beta-lactamases by the main pathogens and conditionally pathogenic microorganisms. aureus (except for methicillin-resistant strains), S.epidermidis (except for methicillin-resistant strains), Listeria spp., Enterococcus spp. Gram-negative aerobes: Bordetella pertussis, Brucella spp., Campylobacter jejuni, E. coli, Gardnerell, v. G., Ginalnereinf , Klebsiella spp., Moraxella catarrhalis, N..gonorrhoeae, N. meningitidis, Pasteurella multocida, Proteus spp., Salmonella spp., Shigella spp., Vibrio cholerae, Yersinia enterocolitica. Anaerobes: Peptococcus spp., Peptococcus spp. , Bacteroides spp., Actinomyces israelii. Quickly absorbed after oral administration (food intake does not affect absorption). The maximum concentration is achieved 1 hour after administration. The maximum plasma concentration after a 1.2 g bolus injection is 105.4 mg / L (for amoxicillin) and 28.5 mg / L (for clavulanic acid). It has a large volume of distribution - high concentrations are found in body fluids and tissues (lungs, pleural, peritoneal, synovial fluid, tonsils, bronchial secretions, prostate gland, peritoneal abscess, muscle tissue, adipose tissue, sinuses, middle ear, etc. .). Peak concentrations in body fluids are observed 1 h after reaching a peak in plasma concentrations. It does not pass through the BBB with uninflamed meninges, passes through the placental barrier and penetrates into breast milk in trace concentrations. Weakly bound to plasma proteins. Amoxicillin is partially metabolized, clavulanic acid undergoes intensive metabolism. Amoxicillin is excreted by the kidneys almost unchanged by tubular secretion and glomerular filtration; clavulanic acid - by glomerular filtration, partly in the form of metabolites. Small amounts are excreted by the intestines and lungs. The elimination half-life is 1-1.5 hours, with severe renal failure it increases to 7.5 (for amoxicillin) and 4.5 hours (for clavulanic acid). It is removed during hemodialysis, slightly - with peritoneal dialysis..